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Zegerid OTC Uses

How Does It Work?

Zegerid OTC belongs to a group of medications called proton pump inhibitors (PPIs). The stomach contains tiny pumps (called proton pumps) that produce acid. Zegerid OTC works by binding to the proton pumps, stopping them from producing acid. PPIs are very effective at decreasing acid production, as they work directly at the acid pumps.
PPI medications can be destroyed by stomach acid before they have a chance to be absorbed by the body. Other PPIs get around this problem by coating the medication with special delayed-release enteric coatings (which protect the medication until it reaches the small intestine).
Zegerid OTC is different; instead of a delayed-release coating, the capsules contain sodium bicarbonate (baking soda) that acts as a buffer. This allows the medication to dissolve immediately without being destroyed by stomach acid.
It is important to note that the medication does not provide immediate benefit, as all PPIs (including Zegerid OTC) can take a few days to start working.

Can Children Use It?

This product has not been approved for use in children, as it has not been adequately studied in individuals under 18 years of age. Additionally, because Zegerid OTC should not be chewed, crushed, or opened and sprinkled on food, it is not an appropriate dosage form for many children.

Off-Label Uses of Zegerid OTC

On occasion, your healthcare provider may recommend Zegerid OTC for treating something other than the conditions listed in this article. This is called an "off-label" use. Some off-label uses for Zegerid OTC may include:
  • Treating ulcers, including stomach ulcers (gastric ulcers) or small intestine ulcers (duodenal ulcers)
  • Preventing ulcers due to nonsteroidal anti-inflammatory medications (NSAIDs)
  • Preventing "stress ulcers" in the seriously ill, such as people hospitalized in an intensive care unit (ICU)
  • Treating pathological hypersecretory conditions, such as:
    • Zollinger-Ellison syndrome
    • Multiple endocrine adenomas
    • Systemic mastocytosis
    • "Short-gut" syndrome.

Zegerid OTC Medication Information

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