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Viokace Warnings and Precautions

People who have a history of bowel problems or kidney disease may not be able to safely use Viokace. There are also some safety precautions for people who have high uric acid in the blood, as well as warnings for those who have gout. Some people may also have an increased risk for developing problems like allergic reactions and other dangerous complications.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Viokace® (pancrelipase) if you have:
  • A history of intestinal blockage or other bowel problems
  • High uric acid in the blood (hyperuricemia)
  • Gout
  • Trouble swallowing tablets
  • Kidney disease, such as kidney failure, or if you are on dialysis
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings for Viokace

Some warnings and precautions to be aware of prior to taking this medication include the following:
  • As with other pancrelipase products, Viokace can cause a condition known as fibrosing colonopathy in rare cases. This condition is potentially serious and may require surgery. It is most likely to occur with very high doses of Viokace. Alert your healthcare provider to any symptoms of this condition, such as unusual or severe:
    • Abdominal (stomach) pain
    • Bloating
    • Trouble passing stool
    • Nausea, vomiting, or diarrhea.
  • Viokace may increase uric acid levels in the blood, which may cause or worsen gout or kidney problems.
  • Swallow the tablets whole, with plenty of liquid. The enzymes in Viokace could irritate the mouth if any residue remains in the mouth.
  • Viokace is derived from the pancreatic glands in pigs. There is a theoretical possibility that the medication could contain viruses or other infectious materials from the pigs, although measures are taken to help prevent this. No cases of pig-related infections from Viokace have ever been reported.
  • People who are allergic to pigs or pig products might also be allergic to Viokace.
  • Viokace is a pregnancy Category C medication, which means it may not be safe for use in pregnancy, although the full risks are currently unknown (see Viokace and Pregnancy).
  • It is unknown whether Viokace passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Viokace and Breastfeeding).

Viokace Medication Information

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