TriLyte and Pregnancy
Because no pregnancy studies have been done on this laxative, it's unclear if TriLyte is completely safe for use in women who are expecting. However, the risk of fetal harm appears to be low, as TriLyte is not expected to be absorbed into the blood. The medication has a pregnancy Category C rating, which means it may be prescribed if the benefits outweigh the risks.
TriLyte® (polyethylene glycol electrolyte solution) is a prescription laxative used to empty the bowel before a colonoscopy. It comes in the form of a powder and is mixed with water before use. At this time, it is unknown if TriLyte is safe for use during pregnancy.
The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans but do appear to cause harm to the fetus in animal studies.
In addition, medicines that have not been adequately studied in pregnant women or animals are automatically given a pregnancy Category C rating.
There is very little information on TriLyte use during pregnancy, as it has not been studied in pregnant animals or women. Because the drug is not expected to be absorbed into the blood in any appreciable amounts after normal use, it would be unlikely to cause fetal harm. However, because of the lack of studies on TriLyte and pregnancy, all potential risks cannot be ruled out.
In general, a pregnancy Category C medicine should be given to a pregnant woman only if the healthcare provider believes that the benefits to the woman outweigh any possible risks to the unborn child. The manufacturer recommends that TriLyte only be given to pregnant women if clearly needed.
It is rare to need a colonoscopy during pregnancy. However, if you do need to have this procedure, your healthcare provider may recommend a medication such as TriLyte to empty your bowel prior to the colonoscopy. This is because it is important for the doctor to get a clear image of the inside of your intestines and any stool or matter remaining in the bowel could block important findings.