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Triamterene-HCTZ Dosing

Triamterene-HCTZ dosing guidelines take various factors into account, such as how a person responds to the drug and if other medications are being taken. In general, triamterene-HCTZ dosages are the same for both high blood pressure and fluid retention. The usual dose for any use is triamterene-HCTZ 25/37.5 mg or triamterene-HCTZ 50/75 mg once daily.

 

An Overview of Triamterene-HCTZ Dosing

The dose of triamterene-HCTZ (Dyazide®, Maxzide®) that your healthcare provider recommends will vary depending on a number of factors, including:
 
  • Other medical conditions you may have
  • Other medications you may be currently taking
  • How you respond to triamterene-HCTZ.
     
As always, do not adjust your triamterene-HCTZ dose unless your healthcare provider specifically instructs you to do so.
 

Triamterene-HCTZ Dosing for All Uses

The recommended dose of triamterene-HCTZ, regardless of the use, is triamterene-HCTZ 25/37.5 mg or triamterene-HCTZ 50/75 mg, taken once daily. Even if you are taking two tablets or capsules per day, it is usually safer to take them both at once instead of splitting them up. Studies have shown that taking the medication twice a day may increase your risk of electrolyte imbalance or kidney problems.
 

General Information on Dosing With Triamterene-HCTZ

Some considerations for people taking triamterene-HCTZ include:
 
  • The medication comes in tablet and capsule form. It is usually taken by mouth once a day.
     
  • You can take triamterene-HCTZ with or without food.
     
  • Triamterene-HCTZ should be taken at the same time each day to maintain even levels of the drug in your blood.
     
  • Because triamterene-HCTZ increases urination, it is best to take it the morning (to avoid needing to get up to use the bathroom throughout the night), unless your healthcare provider instructs you otherwise.
     
  • For the medication to work properly, it must be taken as prescribed. Triamterene-HCTZ will not work if you stop taking it.
     
  • If you are unsure about anything related to triamterene-HCTZ or triamterene-HCTZ dosing in general, talk with your healthcare provider, nurse, or pharmacist. Do not stop taking the drug without first discussing it with your healthcare provider.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;