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Drug Interactions With Triamterene-HCTZ

If certain medications are combined, there is a possibility of negative drug interactions. With triamterene-HCTZ, these interactions can affect the potassium levels in your blood and may increase your risk of side effects. Among the drugs that can potentially cause drug interactions with triamterene-HCTZ are NSAIDs, corticosteroids, and lithium. To prevent these drug interactions with triamterene-HCTZ from occurring, your healthcare provider may adjust your dosages.

An Overview of Drug Interactions With Triamterene-HCTZ

Triamterene-HCTZ (Dyazide®, Maxzide®) can potentially interact with a number of other medicines. Some of the medicines that can lead to triamterene-HCTZ drug interactions include:
  • Amiloride (Midamor®)
  • Amphotericin B (Amphocin®, Abelcet®, AmBisome®, Amphotec®)
  • Angiotensin II receptor blockers (ARBs), such as:


  • Potassium-containing products, such as:
    • Potassium chloride (K-Dur®, Klor-Con®, Micro-K®)
    • Potassium citrate (Urocit-K®, Polycitra-K®)
    • Potassium gluconate
    • Potassium phosphate (Neutra-Phos-K®, K-Phos®)
    • Salt substitutes (used to flavor food)
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Information About Triamterene-HCTZ

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