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Telbivudine

Important Information for Your Healthcare Provider

You should talk with your healthcare provider prior to taking this medication if you have:
 
  • Kidney disease, such as kidney failure (renal failure)
  • Liver disease, other than hepatitis B
  • Had a liver transplant
  • Human immunodeficiency virus (HIV)
  • Hepatitis C or D
  • Any allergies, including to foods, dyes, or preservatives.
 
Also, let your healthcare provider know if you are:
 
 
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 
(Click Precautions and Warnings With Telbivudine to learn more, including information on who should not take the drug.)
 

How Does It Work?

Telbivudine is an antiviral medication. It works by preventing viral cells from multiplying in the body. It does this by blocking a process the virus needs to multiply.
 
When HBV infects a person, it uses the person's own cells to reproduce. However, HBV's genetic information is in the form of RNA, not DNA. So, the virus must first convert its genetic material from RNA to DNA. A special protein called the reverse transcriptase enzyme is necessary for this conversion to occur.
 
Telbivudine resembles building blocks (known as nucleotides) that reverse transcriptase uses to convert RNA into DNA. However, it is just different enough that when used to create DNA, the medication actually stops the DNA from being made. Without DNA, the virus cannot multiply.
 

Telbivudine Drug Information

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