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Warnings and Precautions With Tegaserod

Some Tegaserod Warnings and Precautions

Some precautions and warnings with Tegaserod to be aware of include:
 
  • Tegaserod can cause very severe diarrhea. Severe diarrhea (or diarrhea that lasts a long time) can be dangerous, causing severe dehydration, low blood pressure (hypotension), and fainting. In studies, some people who took tegaserod had diarrhea severe enough to require hospitalization. If you have severe diarrhea while taking tegaserod, contact your healthcare provider right away.
     
  • Tegaserod can interact with certain other medications (see Drug Interactions With Tegaserod).
     
  • Tegaserod is considered a pregnancy Category B medication. This means that tegaserod is probably safe for use during pregnancy. However, because tegaserod has not been studied in pregnant women, the full risks of using tegaserod during pregnancy are not known. Women who are pregnant should take tegaserod only if the benefits of tegaserod outweigh the possible risks to the developing baby. Before using tegaserod during pregnancy, be sure to talk with your healthcare provider about tegaserod's possible risks and benefits, as well as other ways to relieve IBS and constipation during pregnancy (see Zelnorm During Pregnancy for more information).
     
  • It is not known if tegaserod is passed through breast milk. Therefore, if you are breastfeeding or plan to start breastfeeding, be sure to talk with your healthcare provider about the safety of taking tegaserod while nursing. He or she can decide whether taking tegaserod while nursing would be okay for your particular situation.
     
  • Contact your healthcare provider right away if you have new or sudden worsening of abdominal pain (or stomach pain) while taking tegaserod.
     
  • Tegaserod has been reported to cause ischemic colitis, a dangerous condition involving decreased blood flow to the large intestine. If ischemic colitis is severe or lasts too long, the parts of the intestine that are not getting enough blood may be severely damaged. Contact your healthcare provider right away if you have new or sudden worsening of abdominal pain (or stomach pain), rectal bleeding, or bloody diarrhea during treatment with tegaserod. These can be signs of ischemic colitis.
     

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