Drug Interactions With Sunitinib
Taking denosumab with sunitinib could increase your risk for potentially serious infections. Talk to your healthcare provider before taking these medicines together. Also, contact your healthcare provider if you develop any symptoms of an infection, such as fever, chills, aches and pains, or coughing.
Sunitinib may be less effective if it is taken with echinacea. Do not take these medications together unless your healthcare provider tells you otherwise.
Sunitinib may increase the level of everolimus in your blood, potentially increasing your risk for side effects. Your healthcare provider may need to lower your everolimus dosage if you take these medications together.
Grapefruit or Grapefruit Juice
Taking grapefruit juice with sunitinib may increase the level of sunitinib in your body, possibly increasing your risk for side effects. To avoid this possible interaction, do not drink grapefruit juice or eat grapefruit while taking sunitinib, unless your healthcare provider tells you otherwise.
Combining leflunomide with sunitinib may increase your risk for blood cell problems, including abnormally low red blood cells, white blood cells, and platelets. Your healthcare provider will likely monitor you for these problems if you take these medications together.
Live vaccines contain live viruses or bacteria. If you receive a live vaccine while taking sunitinib, you might become infected with the virus or bacteria from the vaccine. Also, live vaccines may be less effective in people taking sunitinib. Talk to your healthcare provider before receiving a vaccination or immunization while taking this medication.