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Rectiv Warnings and Precautions

Because Rectiv is a nitroglycerin medication, it is very important for anyone with a heart problem to discuss the risks with their doctor before starting treatment. Other warnings and precautions apply to people with certain allergies or low blood pressure. You should not use Rectiv if you have severe anemia, high intracranial pressure, or are taking a phosphodiesterase type 5 inhibitor.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using Rectiv™ (nitroglycerin anal ointment) if you have:
  • Low blood pressure (hypotension)
  • Dehydration
  • Anemia
  • Increased intracranial pressure
  • Heart problems of any kind
  • Any allergies, including to food, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also be sure to tell your healthcare provider about all of the medicines you take, including prescription and nonprescription medications, vitamins, and herbal supplements.

Specific Warnings and Precautions With Rectiv

Some warnings and precautions to be aware of with this drug include the following:
  • Rectiv contains nitroglycerin, a drug that affects blood pressure and blood flow throughout the body. It may not be safe for people with certain types of heart problems. If you have any heart problems, discuss this potential risk with your healthcare provider before using this drug.
  • This medication often causes headaches, which can be quite severe. These usually improve over time, as the body gets used to the effects of nitroglycerin.
  • Rectiv can sometimes cause dangerously low blood pressure (hypotension). Alcohol or certain other medications may make this worse (see Rectiv Drug Interactions). People who already have low blood pressure or who are dehydrated are at a higher risk for this complication.
  • In rare cases, some people may be allergic to Rectiv. Let your healthcare provider know if you develop any signs of an allergic reaction, such as:
    • Hives
    • Itching
    • Unexplained swelling
    • Difficulty breathing.
  • Rectiv is a pregnancy Category C medication, which means that it may not be safe for use during pregnancy, although the full risks are currently unknown (see Rectiv and Pregnancy for more information).
  • It is unknown if Rectiv passes through breast milk. Therefore, if you are breastfeeding a child, check with your healthcare provider (or your child's healthcare provider) before using this product (see Rectiv and Breastfeeding).
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Rectiv Medication Information

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