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Primary Biliary Cirrhosis (Cont.)

Symptoms of Primary Biliary Cirrhosis

During the early stages of primary biliary cirrhosis, a person may not even know that his or her liver is being damaged. He or she may not have any symptoms of primary biliary cirrhosis, or notice any physical changes to his or her body. If someone does have primary biliary cirrhosis symptoms, the most common symptoms are itchy skin and fatigue. Other primary biliary cirrhosis symptoms may include:
 
  • Jaundice (yellowing of the eyes and skin)
  • Cholesterol deposits on the skin
  • Fluid retention
  • Dry eyes or dry mouth.
     
Some people with primary biliary cirrhosis also have osteoporosis, arthritis, or thyroid problems.
 
(Click Primary Biliary Cirrhosis Symptoms to learn about other symptoms of this condition, including some more serious symptoms.)
 

Primary Biliary Cirrhosis Diagnosis

Primary biliary cirrhosis is diagnosed through laboratory tests, x-rays, and, in some cases, a liver biopsy (a simple operation to remove a small piece of liver tissue).
 
(Click Diagnosing Primary Biliary Cirrhosis for more information about making a primary biliary cirrhosis diagnosis.)
 

Treatment for Primary Biliary Cirrhosis

Unfortunately, liver damage from primary biliary cirrhosis cannot be reversed. However, treatment may be able to slow further progression and reduce symptoms and complications.
 
Treatment for primary biliary cirrhosis may include:
 
  • Lifestyle changes
  • Medications
  • Liver transplant.
     
Although ursodiol (a medication used to dissolve gallstones) can be beneficial for patients with primary biliary cirrhosis, it does not cure the disease. A liver transplant may be necessary if the liver is severely damaged.
 
(Click Primary Biliary Cirrhosis Treatment for more information on how this condition may be treated.)

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Written by/reviewed by: Arthur Schoenstadt, MD
Last reviewed by: Arthur Schoenstadt, MD