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Ondansetron Oral Soluble Film Dosage

The recommended dosage of ondansetron oral soluble film will depend on your age, the medical condition being treated, and other medications you are taking, among other factors. This medication comes in the form of a small film that quickly dissolves on the tongue. It is taken before surgery, radiation therapy, or chemotherapy to prevent nausea and vomiting.

An Introduction to Your Dosage of Ondansetron Oral Soluble Film

The dose of ondansetron oral soluble film (Zuplenz™) your healthcare provider recommends will vary depending on a number of factors, including:
 
  • Your age
  • The medical condition being treated
  • Other medical conditions you may have
  • Other medications you are taking.
     
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
 

Dosing for After Surgery

The dose of ondansetron oral soluble film for preventing postoperative nausea and vomiting is 16 mg (two 8-mg films) taken one hour before anesthesia is administered.
 

Dosing for Chemotherapy

The dose of ondansetron oral soluble film depends on the type of chemotherapy and how likely it is to cause nausea and vomiting, as follows:
 
  • High-risk chemotherapy: The dosage for high-risk chemotherapy is 24 mg (taken as three 8-mg films) 30 minutes before chemotherapy.
     
  • Medium-risk chemotherapy: The dosage for medium-risk chemotherapy is 8 mg twice daily. The first dosage should be taken 30 minutes before chemotherapy, and the second dose should be taken eight hours after the first one. After that, the medication should be taken twice a day (about every 12 hours) until one to two days after chemotherapy.
     
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Ondansetron Oral Soluble Film Information

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