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Ondansetron Oral Soluble Film Dosage

Dosing for Radiation

The right ondansetron oral soluble film dosage for radiation will depend on the type of radiation:
 
  • Total body irradiation: The dosage for total body irradiation is 8 mg taken one to two hours before radiotherapy each day of radiation treatment.
     
  • Single high-dose fraction radiotherapy to the abdomen: The dosage for this type of radiation is 8 mg taken one to two hours before radiotherapy, followed by 8 mg every eight hours (three times a day) until one to two days after radiation.
     
  • Daily fractionated radiotherapy to the abdomen: The ondansetron oral soluble film dosage for this type of radiation is 8 mg taken each day one to two hours before radiotherapy, followed by two more doses each day (taken every eight hours) during radiation.
     

Dosing for Children

Ondansetron oral soluble film has only been studied in children for medium-risk chemotherapy-associated nausea and vomiting.
 
  • For children 12 years and older, the dosage is the same as for adults.
     
  • For children age 4 through 11, the dosage is 4 mg three times daily. The first dose should be given 30 minutes before the start of chemotherapy. The second dosage should be given four hours after the first one, and the third dose should be given eight hours after the first. For one to two days after chemotherapy, 4 mg should be taken three times a day (about every eight hours).
     

General Information on Taking Ondansetron Oral Soluble Film

Some considerations for people taking ondansetron oral soluble film include the following:
 
  • The medication comes as a small film that dissolves in the mouth.
     
  • Ondansetron oral soluble film should be taken 30 minutes before the start of chemotherapy. Your healthcare provider may recommend that you take additional doses after the first one.
     
  • The medication should be taken one to two hours before radiation. The amount used after radiation will depend on the type of radiation.
     
  • Ondansetron oral soluble film should be taken one hour before surgery begins.
     
  • It can be taken with or without food.
     
  • Place the film on your tongue, where it will dissolve within 4 to 20 seconds. After it has dissolved, swallow (with or without liquid). Wash your hands after taking the dose.
     
  • If you take two or three films for a single dose, make sure to let the first one completely dissolve before taking another one.
     
  • The recommended ondansetron oral soluble film dosage is lower for people who have poor liver function (hepatic function). People with severely impaired liver function should not take more than 8 mg total each day.
     
  • For ondansetron oral soluble film to work properly, you have to take it as prescribed. This medication will not work if you take it differently than how your healthcare provider prescribed it.
     
  • If you are unsure about anything related to your dosage or ondansetron oral soluble film dosing in general, please talk to your healthcare provider, nurse, or pharmacist. Do not stop taking this medication without discussing it first with your healthcare provider.
     
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Ondansetron Oral Soluble Film Information

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