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Important Information for Your Healthcare Provider

You should talk with your healthcare provider prior to taking this medication if you have:
Also, let your healthcare provider know if you are:
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Misoprostol to learn more, including information on who should not take the drug.)

How Does Misoprostol Work?

Misoprostol is a type of prostaglandin, a hormone-like substance found naturally in the body. Prostaglandins help protect the stomach lining from stomach acid and other harmful substances. NSAIDs block the production of prostaglandins in the body, which is part of the reason these drugs increase the risk for ulcers. Misoprostol works to prevent stomach ulcers caused by NSAIDs by protecting the lining of the stomach and decreasing stomach acid secretion.

When and How to Take This Medicine

Some general considerations to keep in mind during treatment with misoprostol include the following:
  • This medication comes in tablet form. It is taken by mouth four times a day.
  • You should take misoprostol after a meal and take your last dose of the day at bedtime.
  • Try to take this medication at the same time each day to keep an even level in your blood.
  • To help prevent an ulcer, you will need to take misoprostol as long as you are taking an NSAID.
  • For the medication to work properly, it must be taken as prescribed.

Misoprostol Drug Information

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