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Misoprostol and Pregnancy

Women should not take misoprostol (Cytotec®) during pregnancy, as this drug can cause fetal harm and other problems. This pregnancy Category X medication can cause contractions of the uterus and uterine bleeding. These reactions can cause premature birth or miscarriage. Also, the drug has been associated with certain birth defects when taken during the first trimester, such as defects of the skull and face.
There are some unapproved reasons a healthcare provider may prescribe misoprostol to a pregnant woman. These "off-label" uses include inducing labor or causing an abortion. However, these uses of the drug may cause a uterine rupture (a tear in the lining of the uterus), which can be potentially dangerous for the mother and child.
(To learn more, click Cytotec and Pregnancy. This Web selection discusses the potentially serious complications misoprostol can cause during pregnancy. It also explains why women taking this drug need to use an effective form of birth control during treatment.)
Pregnancy and Pain
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