People who are about to have a colonoscopy may receive Prepopik to help cleanse the bowels before the procedure. This prescription medication comes as a powder that is mixed with water and taken in two separate doses. Unlike many other bowel-prep products, Prepopik has the lowest amount of solution that you must drink. Side effects may include headaches, nausea, and vomiting.
The sodium picosulfate in this medication is a stimulant laxative. It stimulates the muscular movements of the colon to help clear out the contents. The other active ingredients (magnesium oxide and anhydrous citric acid) combine to form magnesium citrate, an osmotic laxative. Magnesium citrate works by drawing water into the colon, which softens the stool and causes watery bowel movements. The watery bowel movements flush waste from the intestines, cleaning them out.
Clinical studies have shown that Prepopik can effectively cleanse the bowel before a colonoscopy. In these studies, Prepopik was compared to a traditional "big jug" bowel prep medication, which was combined with stimulant laxative tablets. Prepopik was as effective as the traditional regimen.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed December 10, 2012.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind.
Site users seeking medical advice about their specific situation should consult with their own physician. Click