Digestive System Home > What Is Olsalazine Used For?

How Does Olsalazine Work?

Olsalazine belongs to a group of medications called aminosalicylates. The medication is believed to work by inhibiting the production of inflammatory chemicals in the lining of the colon. As a result, it decreases the production of prostaglandins and leukotrienes, chemicals that lead to the inflammation caused by ulcerative colitis.
The olsalazine molecule itself is inactive. However, when it reaches the colon, bacteria enzymes split the olsalazine molecule, releasing the active forms of the medication.

Is Olsalazine Used for Children?

Olsalazine is not approved for use in children. Be sure to talk with your healthcare provider about the risks and benefits of using the drug in children.

Is Olsalazine Used for Off-Label Reasons?

On occasion, your healthcare provider may recommend olsalazine for something other than ulcerative colitis. This is called an "off-label" use. Among these potential off-label olsalazine uses is the treatment of Crohn's disease.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
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