Digestive System Home > Misoprostol

Certain people who take nonsteroidal anti-inflammatory drugs (NSAIDs) may be given misoprostol to help prevent stomach ulcers or other ulcer-related complications. This prescription medicine is a hormone-like substance that helps protect the stomach lining from stomach acid. It comes as tablets that are taken four times a day. Possible side effects include diarrhea, headaches, and stomach pain.

What Is Misoprostol?

Misoprostol (Cytotec®) is a prescription medication approved to prevent stomach ulcers in people taking nonsteroidal anti-inflammatory drugs (NSAIDs). It is used in people who have a risk of developing ulcers or those who are at risk for serious ulcer complications.
 
(Click What Is Misoprostol Used For? for more information on this topic, including possible off-label uses.)
 

Are There Side Effects?

Just like any medicine, misoprostol may cause side effects. However, not everyone who takes the drug will experience problems. In fact, most people tolerate it quite well.
 
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
 
Common side effects of misoprostol include but are not limited to:
 
 
(Click Misoprostol Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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