Most people can safely use most medications, though there is always the risk of having an adverse or allergic reaction. This is true for all types of medicine, including anesthesia. Some examples of minor allergic reactions are itchy eyes, runny nose, or skin rashes. Other people may have a serious reaction called anaphylaxis, which can be fatal.
There's no way for your doctor to know if you will be allergic to medicines that you have never tried. But, your healthcare team will try to find out as much information as they can to help prevent an allergic reaction. They will ask questions about medicines you are taking, about your health in the past, and if you have any allergies already. Be sure to tell your healthcare provider about all of your allergies. This information can help your doctor and other healthcare professionals pick the medicines that are best for you.