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When and How to Take This Medicine

Some general considerations to keep in mind during treatment with linaclotide include the following:
  • Linaclotide comes in the form of a capsule. It is usually taken by mouth once a day.
  • You should take your dose on an empty stomach, at least 30 minutes before your first meal of the day.
  • Do not crush, chew, or open the capsules; make sure to swallow them whole.
  • For the medication to work properly, it must be taken as prescribed.

Dosing Information for Linaclotide

The dose of this medication your healthcare provider recommends may vary, depending on a couple of factors, including:
  • The reason you are taking it
  • Side effects you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
(Click Linaclotide Dosage for more information.)

Drug Interactions

At this time, there are no known drug interactions with this medication (see Drug Interactions With Linaclotide).

What If I Overdose on Linaclotide?

An overdose with linaclotide could cause severe diarrhea or other abdominal (stomach) and intestinal problems. If you happen to overdose on this medication, seek immediate medical attention.
(Click Linzess Overdose for more information.)

Storage Information

Linaclotide should be stored at room temperature, away from moisture. Keep this medication in the original container, tightly closed. The bottle contains a desiccant packet, which helps absorb moisture to keep the medicine dry. Do not remove this packet from the bottle.
Keep this and all other medications out of the reach of children.

Linaclotide Drug Information

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