Were you looking for information about Hirschsprung's Disease? Hirschsprungs is a common alternate spelling of Hirschsprung's disease. Hirschsprung's disease is a medical condition in which the large intestine is affected, and severe constipation is caused as a result. It usually occurs in children before birth. This is a serious disorder that needs to be treated right away. Potential complications of untreated Hirshsprung's disease include infection, bursting of the colon, and even death.