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Causes of Hemochromatosis

Causes of Acquired Hemochromatosis

Acquired hemochromatosis is caused by other medical conditions -- in particular, those in which there is a problem making red blood cells or hemoglobin. Medical conditions that can result in acquired hemochromatosis include:
  • Sideroblastic anemia
  • Thalassemia
  • Porphyria cutanea tarda
  • Alcoholics with chronic liver disease
  • Excessive iron intake
  • Frequent blood transfusions
  • Myelodysplastic syndrome
  • Sickle-cell anemia
  • Hepatitis C.

Causes of Juvenile and Neonatal Hemochromatosis

Juvenile hemochromatosis and neonatal hemochromatosis are two forms of the disease that are not caused by an HFE defect. The causes of hemochromatosis in these types is unknown. The juvenile form leads to severe iron overload, as well as liver and heart disease in adolescents and young adults between the ages of 15 and 30. The neonatal form causes the same problems in newborn infants.

Hemochromatosis Disease

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