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HalfLytely and Bisacodyl Drug Interactions

Several medications, such as certain diuretics, antacids, and nonsteroidal anti-inflammatory drugs, may cause negative drug interactions with HalfLytely and Bisacodyl. Some of these reactions may increase the risk for electrolyte problems. Also, if you take medications within one hour of starting HalfLytely and Bisacodyl, the medications could be flushed out of the gastrointestinal tract before your body has a chance to absorb them.

An Overview of Interactions With HalfLytely and Bisacodyl

HalfLytely® and Bisacodyl (polyethylene glycol electrolyte solution and bisacodyl) is a prescription medication approved to empty the bowels before a colonoscopy. This product may potentially interact with many other medications.
Some of the medications that may lead to HalfLytely and Bisacodyl drug interactions include but are not limited to:
  • Angiotensin-converting enzyme inhibitors (ACE inhibitors), such as:
  • Angiotensin II receptor blockers (ARBs), such as:


  • Antacids (Alternagel®, Gaviscon®, Maalox®, Mylanta®, Tums®, and many others)
  • Diuretics, such as:
  • Nonsteroidal anti-inflammatory drugs (NSAIDs), such as:
  • Oral medications taken within one hour of the first HalfLytely and Bisacodyl dose.

HalfLytely and Bisacodyl Medication Information

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