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GoLYTELY Drug Interactions

If you take any other medications within an hour of your first GoLYTELY dose, you are putting yourself at risk of drug interactions. More specifically, the GoLYTELY solution could flush the other medications out of the gastrointestinal tract before the body has a chance to absorb them, making them ineffective. Your healthcare provider can tell you which medications should be stopped before your procedure.

An Introduction to Interactions With GoLYTELY

GoLYTELY® (polyethylene glycol electrolyte solution) is a prescription medication licensed to cleanse the bowel before a colonoscopy or barium enema x-ray examination. GoLYTELY may interact with other medications taken within one hour of the first dose.
GoLYTELY is an osmotic laxative. It works by drawing water into the colon, which causes frequent, watery bowel movements, thereby emptying the bowel. Any medication taken within one hour of starting GoLYTELY may be flushed out of the gastrointestinal tract before being absorbed by the body.
Avoid taking any oral medications, vitamins, or supplements within one hour of beginning your GoLYTELY dosing and while you are using it. You may take your medications as usual earlier in the day. If you will miss normal medication doses because of GoLYTELY treatment, talk to your healthcare provider or pharmacist about when you should take these medications.
Although not directly an interaction with GoLYTELY, certain drugs should not be taken in the days before or the morning of a colonoscopy. Some medications may even need to be stopped a week prior to the colonoscopy. Be sure to ask your healthcare provider which medications you should continue and which are best avoided in the days leading up to your procedure.

Final Thoughts

It is a good idea to make sure all your healthcare providers have a complete list of all your medications. Therefore, you should always tell your healthcare providers about all medications you take, including prescription drugs, nonprescription drugs, vitamins, and supplements, even if you believe they will not interact with other drugs.

GoLYTELY Medication Information

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