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Ethacrynic Acid

Ethacrynic acid is a type of diuretic used for the treatment of fluid retention. It works by increasing the amount of salt and water that is removed from the blood, which causes a decrease in blood volume. The medication comes in tablet form, and is usually taken once or twice a day. Side effects of ethacrynic acid include nausea, electrolyte imbalance, headache, and hearing problems.

 

What Is Ethacrynic Acid?

Ethacrynic acid (Edecrin®) is a prescription medicine that is used to treat fluid retention due to several causes. It is part of a class of medicines known as diuretics. Because ethacrynic acid is a strong diuretic, it is usually reserved for serious situations when a large amount of fluid needs to be removed from the body.
 
(Click What Is Ethacrynic Acid Used For? for more information, including possible off-label uses of the drug.)
 

Who Makes Ethacrynic Acid?

Ethacrynic acid is made by Aton Pharma.
 

How Does Ethacrynic Acid Work?

Ethacrynic acid is a diuretic, which is commonly referred to as a "water pill." Specifically, it is known as a "loop diuretic," named after the part of the kidneys where it acts (the loop of Henle). The medication works by increasing the amount of salt and water that the kidneys remove from the blood, which is passed out through urine. By increasing the amount of water removed from the blood, ethacrynic acid causes a decrease in blood volume. This, in turn, helps with water retention.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;