Despite the current sterile techniques used for all procedures, infections are a possibility with an upper endoscopy (EGD). If you do develop an infection, the treatment options will vary depending on the location of the infection. Infections can range from very minor ones that are treated only with antibiotics (with or without a few extra days in the hospital) to very major infections requiring surgery. If an infection does develop, your doctor will discuss the treatment options and expected outcomes with you.