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Dyrenium Alternatives
If side effects occur or if your water retention cannot be controlled with Dyrenium, alternatives to the medication are available. These alternatives can include taking other diuretics, limiting your salt and fluid intake, becoming more physically active, and wearing support stockings to reduce fluid retention in the legs. Medicines that are considered Dyrenium alternatives include amiloride, spironolactone, and furosemide.
Dyrenium® (triamterene) is a prescription medicine used for treating water retention. The drug is generally effective in treating the condition, and most people tolerate it well. However, as with all medicines, side effects can occur or it may not completely control water retention. Fortunately, several alternatives to Dyrenium are available.
Alternatives to Dyrenium when treating fluid retention (known medically as edema), include the following:
- Limit your salt and fluid intake
- Wear support stockings to reduce fluid retention in the legs
- Become more active (avoid sitting or standing in the same position for too long)
- Take another diuretic medication, such as:
- Amiloride (Midamor®) or amiloride-HCTZ (Moduretic®)
- Bumetanide (Bumex®)
- Chlorothiazide (Diuril®)
- Chlorthalidone (Thalitone®)
- Ethacrynic acid (Edecrin®)
- Furosemide (Lasix®)
- Hydrochlorothiazide (Esidrix®, HydroDIURIL®, Microzide®, Oretic®)
- Metolazone (Zaroxolyn®)
- Spironolactone (Aldactone®) or spironolactone-HCTZ (Aldactazide®)
- Torsemide (Demadex®)
- Triamterene-HCTZ (Dyazide®, Maxzide®).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD



