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Drug Interactions With Dicyclomine

More Information on Interactions With Dicyclomine

The following sections explain in detail the potentially negative interactions that can occur when dicyclomine is combined with any of the drugs listed above.
 
Acetylcholinesterase Inhibitor Medications
Taking dicyclomine with an acetylcholinesterase inhibitor can make both medications less effective. Your healthcare provider may need to monitor you more closely and adjust your dose of these medications to prevent interactions from occurring.
 
Antacids
Do not take antacids and dicyclomine at the same time, as antacids may interfere with the absorption of dicyclomine.
 
Anticholinergic Drugs
Combining an anticholinergic medication with dicyclomine (which is also an anticholinergic medication) can increase your risk of side effects of dicyclomine, such as dry mouth, constipation, dry eyes, or difficulty passing urine.
 
Metoclopramide
Dicyclomine may make metoclopramide less effective. Check with your healthcare provider before taking these medications together.
 
Glaucoma Medications
Dicyclomine may cause increased eye pressure, possibly making glaucoma medications less effective. People with glaucoma should not take dicyclomine.
 
Pramlintide
Both pramlintide and anticholinergic medications (including dicyclomine) can slow down the movement of food through the digestive tract. Therefore, taking them together can increase the risk of constipation or nausea. Talk with your healthcare provider before combining these medications.
 
Tricyclic Antidepressants
Combining a tricyclic antidepressant with dicyclomine may increase your risk of side effects. Check with your healthcare provider before taking these medications together.
 

Dicyclomine Drug Information

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