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Dicyclomine Dosage
For most people, dicyclomine dosing guidelines call for 20 mg four times daily for the treatment of irritable bowel syndrome. Within a week, your healthcare provider will usually increase your dose to 40 mg four times daily. The recommended dosage of dicyclomine for the injectable form is 20 mg injected into a muscle four times a day.
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The dose of dicyclomine hydrochloride (Bentyl®) that your healthcare provider recommends will vary, depending on a number of factors, including:
- Other medications you may be taking
- How you respond to dicyclomine
- Your age
- Other medical conditions you may have.
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
The recommended starting dose of dicyclomine for irritable bowel syndrome treatment is 20 mg taken by mouth four times daily. It is necessary to start at a low dose in order to help decrease your chance of experiencing bothersome side effects of dicyclomine. Within a week, your healthcare provider may increase your dose to 40 mg four times daily. If your symptoms have not improved within two weeks, you should talk to your healthcare provider about stopping dicyclomine.
Elderly people may be especially susceptible to the side effects of medications like dicyclomine. Lower doses may be recommended for elderly individuals.
Sometimes, people may temporarily not be able to take medications by mouth. This may occur due to surgery, illness, or other situations. In such cases, an injectable form of dicyclomine may be used. The recommended dose is 20 mg injected into a muscle four times daily. This medication cannot be given by IV, as it could cause blood clots if injected into a vein.
Dicyclomine injection should be used only temporarily (for one or two days).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD



