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Colyte Warnings and Precautions

If you are pregnant, thinking of becoming pregnant, or breastfeeding, tell your healthcare provider before using colyte. This medication is not suitable for everyone, and its warnings and precautions should be fully understood before use. For example, colyte should be used with caution in people with ulcerative colitis, an impaired gag reflex, or difficulty swallowing.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking colyte® (polyethylene glycol electrolyte solution) if you have:
  • Difficulty swallowing
  • A hole in the bowel (bowel perforation)
  • Intestinal blockage (obstruction)
  • Nausea, vomiting, abdominal (stomach) pain, and abdominal swelling (distention), which may be signs of a bowel obstruction
  • Gastric retention (a condition in which there is a delayed emptying of stomach contents into the intestines)
  • Inflammatory bowel disease
  • Other bowel problems, such as ulcerative colitis, toxic colitis, toxic megacolon, and ileus
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings With Colyte

Some warnings and precautions to be aware of prior to taking this drug include the following:
  • Do not add any ingredients to colyte except water, as the directions state, including flavorings or other liquids. If you desire flavoring, only use one flavor pack that came with the medication.
  • colyte should be used with caution in people with an inflammatory bowel disease known as ulcerative colitis. If you have this condition, talk to your healthcare provider before using this product.
  • If severe stomach swelling (abdominal distention), bloating, or discomfort occurs during treatment, temporarily stop taking colyte, or try drinking each eight-ounce portion more slowly, until the symptoms lessen. Some temporary abdominal discomfort and swelling are normal when you first start drinking colyte, especially prior to your first bowel movement.
  • People with difficulty swallowing, with an impaired gag reflex, or who otherwise may be at risk of vomiting and potentially breathing in (aspirating) colyte should be closely watched during administration, especially if the laxative is being given through a nasogastric (NG) tube.
  • People with a hole or blockage in the intestines (bowel perforation or obstruction) should not use this medication. If you have symptoms of these conditions, your healthcare provider will need to perform tests to make sure you do not have them before you begin using colyte. Symptoms of a bowel obstruction or perforation may include:
    • Nausea and vomiting
    • Severe abdominal pain
    • Abdominal distention or swelling
    • Abdominal pain and cramping.
  • Rare cases of an allergic reaction have been reported in some people using colyte. If you develop any signs of an allergic reaction, such as a skin rash, hives, or itching, while using this medication, stop taking it and contact your healthcare provider.
  • colyte is likely to react with other oral medications taken within one hour of starting treatment (see Colyte Drug Interactions).
  • colyte is considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy. Talk to your healthcare provider about the risks and benefits of using colyte when pregnant (see Colyte and Pregnancy).
  • It is unknown if colyte passes through breast milk, though it is not thought to do so. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Colyte and Breastfeeding).

Colyte Solution Information

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