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Bumex Drug Interactions

When medicines such as blood pressure medications, NSAIDs, or certain antibiotics are taken with Bumex, drug interactions can occur. Some of these interactions can lead to permanent hearing loss, extremely low blood pressure, or other side effects. Other medicines that can lead to potentially negative drug interactions with Bumex include digoxin, lithium, corticosteroids, probenecid, and salicylates.

 

Bumex Drug Interactions: An Overview

Bumex® (bumetanide) can potentially interact with a number of other medicines. Some of these Bumex drug interactions can include:
 
  • Aminoglycoside antibiotics, such as:
o Amikacin (Amikin®)
o Gentamicin
o Kanamycin (Kantrex®)
o Neomycin (Neo-Fradin®)
o Streptomycin
o Tobramycin
 
  • Corticosteroids, such as:
o Hydrocortisone (Cortef®)
o Dexamethasone (Decadron®, Dexone®, Hexadrol®)
  • Digoxin (Digitek®, Lanoxin®)

 

 
  • Nonsteroidal anti-inflammatory drugs (NSAIDs), such as:
o Diclofenac (Cataflam®, Voltaren®)
o Ibuprofen (Motrin®, Advil®)
o Indomethacin (Indocin®, Indocin SR®)
  • Probenecid (Benemid®, ColBenemid®)
 
  • Salicylates, such as:
o Aspirin (Ecotrin®, Bayer®, Anacin®)
o Choline magnesium trisalicylate (Trilisate®)
o Salsalate (Salflex®, Disalcid®, Amigesic®). 
(Bumex Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;