Bumex and Pregnancy
In animal studies on Bumex and pregnancy, the medication appeared to cause an increase in miscarriages and also slowed down the growth and development of fetal rats and rabbits. Therefore, the FDA has classified it as a pregnancy Category C medication. If you are taking Bumex and pregnancy occurs, your healthcare provider will consider the benefits and risks, and the drug will be continued only if absolutely necessary.
Bumex® (bumetanide) is a pregnancy Category C medicine, which means it could potentially cause harm to your unborn child.
The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that show side effects to the fetus in animal studies but for which no human studies in pregnant women have been done. A pregnancy Category C medicine may still be given to a pregnant woman if the healthcare provider believes that the benefits to the mother outweigh the possible risks to the unborn child.
In animal studies, very high doses of Bumex caused increased miscarriages. Animal studies have also shown that the drug can slow down the growth and development of fetal rats and rabbits. However, it is important to note that animals do not always respond to medicines in the same way that humans do.
In general, Bumex should be used in pregnant women only when absolutely necessary. The drug should not be used to treat high blood pressure during pregnancy.
If you are taking Bumex and pregnancy occurs, or if you are thinking of becoming pregnant while taking the drug, let your healthcare provider know. He or she will consider the benefits and risks of taking Bumex during pregnancy before making a recommendation for your particular situation.