How Does Balsalazide Work?
Balsalazide belongs to a group of medications called aminosalicylates. It is thought that balsalazide works by inhibiting the production of inflammatory chemicals in the lining of the
colon. The medication decreases the production of prostaglandins and leukotrienes, chemicals that lead to inflammation.
The balsalazide molecule itself is inactive. However, when it reaches the colon, bacteria enzymes split the balsalazide molecule, releasing the active forms of the medication.
Is Balsalazide Used for Children?
Balsalazide is approved to treat
ulcerative colitis in children five years of age and older. Be sure to talk with your healthcare provider about the risks and benefits of using the drug in children.
Is Balsalazide Used for Off-Label Reasons?
On occasion, your healthcare provider may recommend balsalazide for something other than ulcerative colitis. This is called an "
off-label" use. Among these potential off-label balsalazide uses is the treatment of
Crohn's disease.
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