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Precautions and Warnings With Alosetron

Who Should Not Take Alosetron?

You should not take alosetron if you:
  • Are currently constipated or are constipated most of the time.
  • Have had serious problems due to constipation.
  • Have had an intestinal blockage (obstruction), narrowing of the intestines (stricture), a tear in the intestines (perforation), or widening of the intestines (toxic megacolon).
  • Have had ischemic colitis (problems with blood flow to your intestines).
  • Have had a blood clot.
  • Have a blood-clotting disorder.
  • Have had Crohn's disease.
  • Have had ulcerative colitis.
  • Have had diverticulitis.
  • Have severe liver disease.
  • Do not understand the Alosetron Patient Acknowledgement Form or will not follow the instructions in it.
  • Are allergic to Lotronex, alosetron, or any of the inactive components used to make the medication. Your healthcare provider or pharmacist has a list of the inactive ingredients. 

Final Thoughts

There are a number of situations in which alosetron should not be used, along with several warnings and precautions people should be aware of before beginning treatment. However, it is possible that not all of these issues were discussed in this article. Therefore, you should talk with your healthcare provider about the specific safety concerns that may apply to you.

Alosetron Drug Information

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