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Alosetron Side Effects

Let your healthcare provider know right away if you are taking alosetron and experience side effects like blood in your stools, inability to have a bowel movement, or swelling of the throat. These and other serious problems can occur with this medication and require urgent medical treatment. In most cases, however, adverse reactions tend to be minor and include things like bloating, gas, and nausea.

An Introduction to Side Effects of Alosetron

As with any medicine, alosetron hydrochloride (Lotronex®) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in many cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with alosetron. Your healthcare provider can discuss a more complete list with you.)
 

Serious Alosetron Side Effects

Some alosetron side effects are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
 
  • Constipation or an inability to have a bowel movement
  • Signs of a serious problem known as ischemic colitis (reduced blood flow to the bowel), such as:
    • Rectal bleeding
    • Bloody diarrhea
    • Bright red, bloody, or tarry-looking stools
    • Abdominal (stomach) pain that is new or worse than pain you previously had 
 
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.
 

Alosetron Drug Information

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